When I open lightroom 3 a window opens informing me that an up grade is available.
When I attempt to click on the upgrade the screen turns a gray sheen and the program shuts down.
Check case No. 0182835847
I've tried all previous instructions to no avail.
I'm not sure why this is happening for you, but to work around it you could just go to adobe.com and download the latest Lightroom build - download the trial. Then, uninstall your current Lightroom build and install the latest build. That process won't touch your catalog or registration, so when you install the build, it should pick up on your serial number, and let you continue as usual.