With Lightroom 4.1, my Wacom Intuos 5's customized ExpressKeys are no longer working, and instead are using default ExpressKeys from the "All Other" application entry. I'm using Mac OS X 10.7.4; Wacom driver 6.3.1w2 (latest). I did not have this problem with LR 4.1 RC1 or LR 4.1 RC2. I've tried deleting the LR4 entry in Wacom's settings, and re-inserted LR4 in Wacom's settings, but this did not help; restarting the computer didn't help either. I have confirmed that customized ExpressKeys are working in other programs such as Firefox.