Is this a mirrorless camera or a DSLR?
Mirrorless cameras usually have lens profile information embedded in each raw file so Adobe just uses that and no external profile needs to be enabled.
DSLRs typically don't have any information in the raw files so you would have to enable an external profile, which may or may not exist.
If you have a mirrorless camera, turn OFF the Enable Profile Corrections checkbox then look for an i in a circle at the bottom of the lens corrections area and click that I to see if any built-in profile is being used and what sorts of corrections it's doing.
Or are you trying to correct a non-raw file (JPG, PSD, TIF) and no profile exists because most are for raw files, only?
Also the only 100-300 lens profiles I see from Adobe are F4, not F4.5-5.6