I have an open photoshop file and every time I attempt to save it i get an error that it can't save due to a program error. I have tried to save to three different hard disks, as both PSD or TIFF. I also deleted some of the layers to make it smaller. Meanwhile I copied one of the layers to a brand new file, and was able to save that file without any problem. I currently still have this file open so I don't lose all my edits.