This conversation has been merged. Please reference the main conversation: Lightroom Classic: The picture panel goes black and the program crashes
Closing and restarting Lightroom will fix the issue, but it returns if I go into the LIbrary module, and then select a different photo to develop.
Disabling GPU acceleration is the only way to definitively fix the issue. I am working with 46 MP files on a 2560 x 1440 monitor, disabling the GPU is unacceptably slow.
I reinstalled Lightroom CC (2015) and it does not have this issue, I can use GPU acceleration without a problem.
I bought a new video card (Radeon RX 580) and updated with the latest drivers in an attempt to fix this issue.
Interestingly enough, if I use the crop tool inside develop mode, the photo renders perfectly fine.