Lightroom 6. After processing photos, closing the program and reopening it, the processed photos are no longer processed in several area's and have to be reprocessed. Tone setting, except Exposure (that is okay), Detail settings and Lens Corrections setting. In fact I have to re-synchronize the main folder to get back the photograph folder. Lightroom is set to automatically write changes to the XMP files. The only thing I can think of is using the graphics processor might not write to the XMP files in a timely manor.