In CC 2018 I experience that my keyboard shortcuts doesn't always respond. Ths is on PC. I had this problem before in previous versions, but it has become much more prominent in CC2018. What happens in particular is that when I do a certain type of shortcut command such as flatten image, duplicate layer or whatever nothing happens. Previously I experienced this a lot when I wanted to switch from Eraser (E) back to Brush (B). But now it happens to any kind of shortcut. And nothing works until I make a command change like changing back to Brush by clicking the icon. Then shortcuts will work again.