Lightroom: Add 10-bit support for end-to-end 10-bit workflow. That is, Application->Driver->Graphics Card->Monitor for true 10-bit color. At the moment, all that's missing is the application. CS5 supports 10-bit color, why not Lightroom?
What would be interesting to know is WHY Adobe has limited Lightroom in this way. There must be a justifiable reason otherwise I am sure 10 bit would have been enabled. However, it is definitely a desirable attribute and I would add my voice to the request for a full 10 bit monitor output.