Have a way to save a layout. Lightroom is spastic when it comes to changing what show up and what gets hidden. It would be nice to be able to click on a layout name to get stuff BACK TO THE WAY IT WAS BEFORE LR F'ED IT UP!
Wow - I actually found a way to get this posted. In spite of 99.99% of adobe's site dedicated to sales/bs, and anything to do with support buried so deep that only really pissed off users will dig deep enough to find a relevant link.
I have converted this to a feature request. It would help if you could spell out specifically which items get hidden, misplaced or otherwise altered. There may be an existing solution we could point you to.