Lightroom Classic: Corrupting large PSD

This also happened to me last night. I could clearly see my thumbnail image however, when trying to open my file is PS it looked exactly like Seanhoytart-dot-arts image.

How big is your file? Could you post it for us to troubleshoot? Have you tried disabling Preferences > Performance... "Use Graphics Processor"?

I do have autowrite XMP on. I remember seeing the thumbnail and a low-quality render (maybe cache). Does "Export" also trigger a header metadata write? I'm running an fsck_hfs on the 8TB volume looking for bad sectors. So far, this is the first photo that's been corrupted. If no bad sectors, I wonder if it was a race condition bug that rarely shows up but did here to my large filesize combined with an export command before the 1:1 preview was completed. If so, maybe there's a way to rebuild the header so the photograph is rendered correctly? Also, if it was bad sectors, wouldn't that be bits and pieces of bad data in the image rather than a full destruction of the entire PSD?

I have to admit I am more than a little curious as to how you created a PSD file that is ~10 GB in size.  PSD has a limit of 2 GB. Normally when people get over the 2GB limit they are forced to use the PSB format. 

How was this file created?

Ah, didn't really even occur to me that it was massive file size. It's 10 aligned layers at 24078 x 15047 into a smart object with median stack mode (super-resolution). Maybe the corruption ballooned the file size? I can probably rebuild it. 

Drive appears to be fine. The only thing that makes sense is:

1. Created the layered PSD in Photoshop, saved as PSD. PSD requirement = <2GB
2. Imported into Lightroom. Early Feb 2020.
3. Opened LR March 2020, tried to load the image and then export a smaller JPG render of the PSD. 
4. Saw the low-res preview, saw the thumbnail. LR threw error, didn't screencap.
5. PSD file ballooned to almost 10GB. (didn't catch that)
6. PSD file now static garbage in LR, PS, and all other apps. 

I didn't change the file extension from PSB to PSD. It must have been created at < 2GB for me to import into LR. 

That is good news that the drive appears OK.   Just as. a gut check, do you have any other PSDs on your drive that are > 2GB?

Just checked. All others are < 2GB. I might chalk this up to user error somehow, but I'm wary about dismissing it given the half dozen other game-stopping errors I'm running into this past week. Is this LR update bonked? 

Not knowing what those 'game stoppers' are it is hard to comment but in general, this release is cleaner than average from the traffic I monitor. 

I don't have time today to detail but wanted to search to see if it's been documented yet: HDR merge stalls out. Auto-stacking isn't working correctly. BIG ONE: Import dialog is doing partial imports from SD card. Also: Crop tool takes 5-10 seconds to engage (probably because of how the photo is passed to GPU - Radeon VII?)

Sorry, it should read: 24078 x 15047 px

What about the file size?   9.84GB is larger than what PSD supports.

There is a 16384 px long edge limit that prevents 1:1 previews from being built. Add your 'Me To' vote at the below report for this issue.

https://feedback.photoshop.com/photoshop_family/topics/lightroom-classic-preview-size-limit