I’m Pretty sad

Photoshop: CS6 / CC Keyboard shortcuts not responding Mavericks MacOS 10.9

Since Installing Mavericks on my mac pro, the keyboard shortcuts, such as zooming in/out, undo etc, intermittently do not respond.
I have to click on another tool in the tool bar to get the keyboard to respond again.
The problem returns intermittently and seemingly not as a result of the Auto Save function.
My mac pro 15" has 8gb of ram which is more than enough for the type of work I do.I am an illustrator who primarily works around the brush tool.
Have tried disabling Graphics Processor and restarting, but this does not resolve the issue.

Any help would be most appreciated.
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